The Fetch API is a modern way to make network requests in JavaScript, replacing older methods like XMLHttpRequest. It simplifies the process of fetching data from a server and handling responses. With Fetch, you use the fetch function, which returns a Promise that resolves to the Response object representing the response to the request. This object provides methods to access the response data, such as json() for parsing JSON data, text() for plain text, and blob() for binary data. By chaining these methods, you can handle the data in various formats and integrate it into your application. The Fetch API also supports advanced features like request and response headers, handling different HTTP methods, and managing errors more gracefully, making it a powerful tool for modern web development.